PDBe 2re9

X-ray diffraction
2.1Å resolution

Crystal structure of TL1A at 2.1 A

Released:
Source organism: Homo sapiens
Primary publication:
X-ray crystal structure of TNF ligand family member TL1A at 2.1A.
Biochem. Biophys. Res. Commun. 364 1-6 (2007)
PMID: 17935696

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 15, secreted form Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 181 amino acids
Theoretical weight: 20.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95150 (Residues: 72-251; Coverage: 72%)
Gene names: TL1, TNFSF15, VEGI
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 114.911Å b: 114.911Å c: 119.346Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.253
Expression system: Escherichia coli BL21(DE3)