2r2q

X-ray diffraction
1.65Å resolution

Crystal structure of human Gamma-Aminobutyric Acid Receptor-Associated Protein-like 1 (GABARAP1), Isoform CRA_a

Released:
Source organism: Homo sapiens
Entry authors: Tempel W, Paramanathan R, Davis T, Mujib S, Butler-Cole C, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid receptor-associated protein-like 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 110 amino acids
Theoretical weight: 13.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H0R8 (Residues: 3-111; Coverage: 93%)
Gene names: GABARAPL1, GEC1
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ DW
Spacegroup: P1
Unit cell:
a: 36.86Å b: 38.193Å c: 45.746Å
α: 111.09° β: 95.91° γ: 108.05°
R-values:
R R work R free
0.201 0.2 0.234
Expression system: Escherichia coli BL21(DE3)