X-ray diffraction
2.59Å resolution

Crystal Structure of ALIX/AIP1 in complex with the YPDL Late Domain


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Programmed cell death 6-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 697 amino acids
Theoretical weight: 78.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8WUM4 (Residues: 2-698; Coverage: 80%)
Gene names: AIP1, ALIX, KIAA1375, PDCD6IP
Sequence domains: BRO1-like domain
Structure domains:
p9 Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 950 Da
Source organism: Equine infectious anemia virus (ISOLATE WYOMING)
Expression system: Not provided
  • Canonical: P69732 (Residues: 456-463; Coverage: 2%)
Gene name: gag

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2
Unit cell:
a: 146.383Å b: 98.57Å c: 72.799Å
α: 90° β: 107.07° γ: 90°
R R work R free
0.226 0.223 0.286
Expression systems:
  • Escherichia coli
  • Not provided