› 2qzh

Electron Microscopy
14Å resolution

SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF

Released:
DOI: 10.2210/pdb2qzh/pdb
PDB entry 2qzh coloured by chain, front view.
PDB entry 2qzh coloured by chain, side view.
PDB entry 2qzh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Interaction of decay-accelerating factor with coxsackievirus B3.
Hafenstein S, Bowman VD, Chipman PR, Bator Kelly CM, Lin F, Medof ME, Rossmann MG
J Virol 81 12927-35 (2007)
PMID: 17804498
Related structures: EMD-1412

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139968 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement decay-accelerating factor Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.35 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P08174 (Residues: 96-222; Coverage: 37%)
Gene names: CD55, CR, DAF
Sequence domains: Sushi repeat (SCR repeat)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 14Å
Relevant EMDB volumes: EMD-1412
Expression system: Komagataella pastoris

Quick links

Citations

6 review citations

Selective inhibitors of picornavirus replication.
De Palma et al. (2008)
5 more

2 mentions without citation

Interaction of decay-accelerating factor with coxsackievirus B3.
Hafenstein et al. (2007)
1 more