2qpw

X-ray diffraction
1.79Å resolution

Methyltransferase domain of human PR domain-containing protein 2

Released:

Function and Biology Details

Reaction catalysed:
(1a) S-adenosyl-L-methionine + a [histone H3]-L-lysine(9) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(9)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PR domain zinc finger protein 2 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13029 (Residues: 2-148; Coverage: 9%)
Gene names: KMT8, PRDM2, RIZ
Sequence domains: SET domain
Structure domains: SET domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 36.462Å b: 51.196Å c: 70.887Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.168 0.222
Expression system: Escherichia coli