2qor

X-ray diffraction
1.8Å resolution

Crystal structure of Plasmodium vivax guanylate kinase

Released:
Source organism: Plasmodium vivax
Entry authors: Merritt EA, Le Trong I, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Reaction catalysed:
ATP + GMP = ADP + GDP
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Guanylate kinase Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 23.95 KDa
Source organism: Plasmodium vivax
Expression system: Escherichia coli
UniProt:
  • Canonical: A5K709 (Residues: 1-196; Coverage: 100%)
Gene name: PVX_099895
Sequence domains: Guanylate kinase
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6522
Unit cell:
a: 43.535Å b: 43.535Å c: 342.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.2 0.227
Expression system: Escherichia coli