› 2qca

X-ray diffraction
1.33Å resolution

A New Crystal Form of Bovine Pancreatic RNase A in Complex with 2'-Deoxyguanosine-5'-monophosphate

Released:
DOI: 10.2210/pdb2qca/pdb
PDB entry 2qca coloured by chain, front view.
PDB entry 2qca coloured by chain, side view.
PDB entry 2qca coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.
Larson SB, Day JS, Cudney R, McPherson A
Acta Crystallogr Sect F Struct Biol Cryst Commun 63 728-33 (2007)
PMID: 17768339

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand DGP 2 x DGP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P31
Unit cell:
a: 55.08Å b: 55.08Å c: 39.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.125 0.119 0.177

Quick links

Citations

2 citation in other articles

The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding.
Doucet et al. (2010)
1 more

1 mention without citation

A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.
Larson et al. (2007)