2qac

X-ray diffraction
1.7Å resolution

The closed MTIP-MyosinA-tail complex from the malaria parasite invasion machinery

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-181897 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
EF-hand domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.7 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I4W8 (Residues: 61-204; Coverage: 71%)
Gene name: PF3D7_1246400
Sequence domains:
Structure domains: EF-hand
Myosin-A Chain: T
Molecule details ›
Chain: T
Length: 15 amino acids
Theoretical weight: 1.84 KDa
Source organism: Plasmodium yoelii yoelii
Expression system: Not provided
UniProt:
  • Canonical: Q7RQ71 (Residues: 803-817; Coverage: 2%)
Gene names: MyoA, PY01232

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2, SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 37.217Å b: 54.12Å c: 76.326Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.167 0.228
Expression systems:
  • Escherichia coli
  • Not provided