PDBe 2q98

X-ray diffraction
2.7Å resolution

X-ray structure of a prolactin antagonist

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prolactin Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 22.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01236 (Residues: 38-227; Coverage: 96%)
Gene name: PRL
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: I4
Unit cell:
a: 122.59Å b: 122.59Å c: 28.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.211 0.302
Expression system: Escherichia coli BL21(DE3)