PDBe 2q97

X-ray diffraction
2.5Å resolution

Complex of mammalian actin with toxofilin from toxoplasma gondii


Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:
Toxofilin Chain: T
Molecule details ›
Chain: T
Length: 129 amino acids
Theoretical weight: 14.78 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9NG25 (Residues: 69-196; Coverage: 58%)
Gene name: toxofilin

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P4122
Unit cell:
a: 54.523Å b: 54.523Å c: 363.1Å
α: 90° β: 90° γ: 90°
R R work R free
0.231 0.229 0.284
Expression system: Escherichia coli BL21(DE3)