X-ray diffraction
2.4Å resolution

2.4 angstrom crystal structure of PPAR gamma complexed to BVT.13 without co-activator peptides


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Peroxisome proliferator-activated receptor gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 274 amino acids
Theoretical weight: 31.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P37231 (Residues: 233-505; Coverage: 54%)
Gene names: NR1C3, PPARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 92.348Å b: 62.033Å c: 118.132Å
α: 90° β: 102.29° γ: 90°
R R work R free
0.212 0.206 0.264
Expression system: Escherichia coli