2pzi

X-ray diffraction
2.4Å resolution

Crystal Structure of Protein kinase PknG from Mycobacterium tuberculosis in Complex with Tetrahydrobenzothiophene AX20017

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PknG Chains: A, B
Molecule details ›
Chains: A, B
Length: 681 amino acids
Theoretical weight: 74.18 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WI73 (Residues: 74-750; Coverage: 90%)
Gene names: MTCY22G10.06c, Rv0410c, pknG
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P65
Unit cell:
a: 122.553Å b: 122.553Å c: 243.749Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.183 0.233
Expression system: Escherichia coli BL21(DE3)