X-ray diffraction
2.02Å resolution

Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP


Function and Biology Details

Reaction catalysed:
ITP + H(2)O = IMP + diphosphate

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
dITP/XTP pyrophosphatase Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 23.34 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
  • Canonical: P52061 (Residues: 1-197; Coverage: 100%)
Gene names: JW2921, b2954, rdgB, yggV
Sequence domains: Ham1 family
Structure domains: Maf protein

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P43212
Unit cell:
a: 77.941Å b: 77.941Å c: 81.073Å
α: 90° β: 90° γ: 90°
R R work R free
0.195 0.192 0.253
Expression system: Escherichia coli