› 2pso

X-ray diffraction
2.8Å resolution

Human StarD13 (DLC2) lipid transfer and protein localization domain

Released:
DOI: 10.2210/pdb2pso/pdb
PDB entry 2pso coloured by chain, front view.
PDB entry 2pso coloured by chain, side view.
PDB entry 2pso coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Comparative structural analysis of lipid binding START domains.
Thorsell AG, Lee WH, Persson C, Siponen MI, Nilsson M, Busam RD, Kotenyova T, Schüler H, Lehtiö L
PLoS One 6 e19521 (2011)
PMID: 21738568

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195211 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
StAR-related lipid transfer protein 13 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 237 amino acids
Theoretical weight: 26.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y3M8 (Residues: 903-1113; Coverage: 19%)
Gene names: DLC2, GT650, STARD13
Sequence domains: START domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P43
Unit cell:
a: 78.24Å b: 78.24Å c: 212.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.244
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Early steps in steroidogenesis: intracellular cholesterol trafficking.
Miller et al. (2011)
16 more

6 mentions without citation

Comparative structural analysis of lipid binding START domains.
Thorsell et al. (2011)
5 more