PDBe 2pe8

X-ray diffraction
2Å resolution

Crystal structure of the UHM domain of human SPF45 (free form)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Splicing factor 45 Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96I25 (Residues: 301-401; Coverage: 25%)
Gene names: RBM17, SPF45
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: F222
Unit cell:
a: 63.9Å b: 90.2Å c: 99.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.231 0.243
Expression system: Escherichia coli