X-ray diffraction
1.54Å resolution

Crystal structure of p53DBD(R282Q) at 1.54-angstrom Resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 24.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P04637 (Residues: 94-292; Coverage: 51%)
  • Best match: P04637-9 (Residues: 1-160)
Gene names: P53, TP53
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 34.9Å b: 35.2Å c: 41.6Å
α: 111.8° β: 94.9° γ: 112.4°
R R work R free
0.193 0.191 0.232
Expression system: Escherichia coli BL21(DE3)