PDBe 2pbn

X-ray diffraction
1.7Å resolution

Crystal structure of the human tyrosine receptor phosphate gamma

Released:

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-type tyrosine-protein phosphatase gamma Chain: A
Molecule details ›
Chain: A
Length: 313 amino acids
Theoretical weight: 36.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P23470 (Residues: 820-1130; Coverage: 22%)
Gene names: PTPG, PTPRG
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3221
Unit cell:
a: 107.338Å b: 107.338Å c: 67.757Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.208 0.234
Expression system: Escherichia coli BL21(DE3)