PDBe 2p4l

Solution NMR

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iota-conotoxin RXIA Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 4.99 KDa
Source organism: Conus radiatus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z094 (Residues: 1-46; Coverage: 100%)
Sequence domains: Conotoxin I-superfamily

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: simulated annealing
Chemical shifts: BMR15174  
Expression system: Escherichia coli