2oq0

X-ray diffraction
2Å resolution

Crystal Structure of the First HIN-200 Domain of Interferon-Inducible Protein 16

Released:
Source organism: Homo sapiens
Entry authors: Lam R, Liao JCC, Ravichandran M, Ma J, Tempel W, Chirgadze NY, Arrowsmith CH, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-interferon-inducible protein 16 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 206 amino acids
Theoretical weight: 24.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16666 (Residues: 192-393; Coverage: 26%)
Gene names: IFI16, IFNGIP1
Sequence domains: HIN-200/IF120x domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 43.335Å b: 88.959Å c: 112.831Å
α: 90° β: 99.37° γ: 90°
R-values:
R R work R free
0.211 0.208 0.26
Expression system: Escherichia coli