X-ray diffraction
2.5Å resolution

Rat pp1c gamma complexed with mouse inhibitor-2


Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Chains: A, B
Molecule details ›
Chains: A, B
Length: 329 amino acids
Theoretical weight: 37.86 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
  • Canonical: P63088 (Residues: 2-323; Coverage: 100%)
Gene name: Ppp1cc
Sequence domains:
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Protein phosphatase inhibitor 2 Chains: I, J
Molecule details ›
Chains: I, J
Length: 206 amino acids
Theoretical weight: 23.15 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
  • Canonical: Q9DCL8 (Residues: 1-206; Coverage: 100%)
Gene name: Ppp1r2
Sequence domains: Protein phosphatase inhibitor 2 (IPP-2)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 96.267Å b: 103.234Å c: 149.992Å
α: 90° β: 90° γ: 90°
R R work R free
0.197 0.194 0.235
Expression system: Escherichia coli BL21