2nxp

X-ray diffraction
2.17Å resolution

Structure of NTD2 domain of the human TAF5 subunit of TFIID

Released:
Source organism: Homo sapiens
Primary publication:
Structural analysis and dimerization potential of the human TAF5 subunit of TFIID.
Proc. Natl. Acad. Sci. U.S.A. 104 1189-94 (2007)
PMID: 17227857

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription initiation factor TFIID subunit 5 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 156 amino acids
Theoretical weight: 18.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15542 (Residues: 188-343; Coverage: 20%)
Gene names: TAF2D, TAF5
Sequence domains: WD40 associated region in TFIID subunit, NTD2 domain
Structure domains: TFIID subunit TAF5, NTD2 domain

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 93.62Å b: 61.829Å c: 133.357Å
α: 90° β: 105.16° γ: 90°
R-values:
R R work R free
0.215 0.213 0.263
Expression system: Escherichia coli