PDBe 2n9x

Solution NMR

LC3 FUNDC1 complex structure

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Microtubule-associated proteins 1A/1B light chain 3B Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 14.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GZQ8 (Residues: 1-120; Coverage: 96%)
Gene names: MAP1ALC3, MAP1LC3B
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
FUN14 domain-containing protein 1 Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 2.07 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8IVP5 (Residues: 10-26; Coverage: 11%)
Gene name: FUNDC1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 3%
Refinement method: simulated annealing
Chemical shifts: BMR25919  
Expression systems:
  • Escherichia coli
  • Not provided