Solution NMR

Solution structure of complex between DNA G-quadruplex and G-quadruplex recognition domain of RHAU


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
ATP-dependent DNA/RNA helicase DHX36 Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H2U1 (Residues: 53-70; Coverage: 2%)
Gene names: DDX36, DHX36, KIAA1488, MLEL1, RHAU
Molecule details ›
Chain: B
Length: 18 nucleotides
Theoretical weight: 5.73 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 23%
Refinement method: DGSA-distance geometry simulated annealing, distance geometry, molecular dynamics
Chemical shifts: BMR25582  
Expression systems:
  • Escherichia coli
  • Not provided