2m9a

Solution NMR

Solution NMR Structure of E3 ubiquitin-protein ligase ZFP91 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7784A

Released:
Source organism: Homo sapiens
Entry authors: Pederson K, Shastry R, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Prestegard JH, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase ZFP91 Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96JP5 (Residues: 370-456; Coverage: 15%)
Gene names: FKSG11, ZFP91, ZNF757
Sequence domains: Zinc finger, C2H2 type
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing
Chemical shifts: BMR19288  
Expression system: Escherichia coli