2m8r

Solution NMR

Pre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Syntaxin-1A Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.33 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P32851 (Residues: 183-288; Coverage: 37%)
Gene names: Sap, Stx1a
Sequence domains: SNARE domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: distance geometry, simulated annealing
Chemical shifts: BMR19266  
Expression system: Escherichia coli