2m5m

Hybrid

Atomic-resolution structure of a triplet cross-beta amyloid fibril

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo 1368-mer (preferred)
homo dodecamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 11 amino acids
Theoretical weight: 1.2 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P02767 (Residues: 125-135; Coverage: 9%)
Gene names: Tt, Ttr

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Experimental Method: Electron Microscopy, Solid-state NMR
Resolution: 12.2Å
Relevant EMDB volumes: EMD-2323
Expression system: Not provided