Solution NMR

The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2

Source organism: Homo sapiens
Entry authors: Surya W, Li Y, Millet O, Diercks T, Torres J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Integrin alpha-L Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P20701 (Residues: 1082-1128; Coverage: 4%)
Gene names: CD11A, ITGAL
Sequence domains: Integrin alpha cytoplasmic region
Structure domains: Bicelle-embedded integrin alpha(iib) transmembrane segment

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Chemical shifts: BMR18958  
Expression system: Escherichia coli BL21