› 2m3b

Solid-state NMR

Serine 16 phosphorylated phospholamban pentamer, Hybrid solution and solid-state NMR structural ensemble

Released:
DOI: 10.2210/pdb2m3b/pdb
PDB entry 2m3b coloured by chain, ensemble of 20 models, front view.
PDB entry 2m3b coloured by chain, ensemble of 20 models, side view.
PDB entry 2m3b coloured by chain, ensemble of 20 models, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Structural dynamics and topology of phosphorylated phospholamban homopentamer reveal its role in the regulation of calcium transport.
Vostrikov VV, Mote KR, Verardi R, Veglia G
Structure 21 2119-30 (2013)
PMID: 24207128

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158177 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cardiac phospholamban Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 52 amino acids
Theoretical weight: 6.18 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61015 (Residues: 1-52; Coverage: 100%)
Gene name: PLN
Sequence domains: Phospholamban
Structure domains: Phospholamban

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 5 x SEP

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 2%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.
Chipot et al. (2018)
1 more

4 mentions without citation

Solution NMR: A powerful tool for structural and functional studies of membrane proteins in reconstituted environments.
Puthenveetil et al. (2019)
3 more