2ltw

Solution NMR

YAP WW1 in complex with a Smad7 derived peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcriptional coactivator YAP1 Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P46937 (Residues: 170-205; Coverage: 7%)
Gene names: YAP1, YAP65
Sequence domains: WW domain
Mothers against decapentaplegic homolog 7 Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O15105 (Residues: 205-217; Coverage: 3%)
Gene names: MADH7, MADH8, SMAD7

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 43%
Refinement method: torsion angle dynamics
Chemical shifts: BMR18499  
Expression systems:
  • Escherichia coli BL21
  • Not provided