PDBe 2lr8

Solution NMR

Solution NMR Structure of CASP8-associated protein 2 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8150A

Source organism: Homo sapiens
Entry authors: Pulavarti S, Sathyamoorthy B, Eletsky A, Sukumaran DK, Lee D, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
CASP8-associated protein 2 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9UKL3 (Residues: 1916-1982; Coverage: 3%)
Gene names: CASP8AP2, FLASH, KIAA1315, RIP25
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: torsion angle dynamics
Chemical shifts: BMR18352  
Expression system: Escherichia coli BL21(DE3)