2l9r

Solution NMR

Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A

Released:
Source organism: Homo sapiens
Entry authors: Liu G, Xiao R, Lee H-W, Hamilton K, Ciccosanti C, Wang HB, Acton TB, Everett JK, Huang YJ, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein Nkx-3.1 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 8.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99801 (Residues: 132-189; Coverage: 25%)
Gene names: NKX3-1, NKX3.1, NKX3A
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: distance geometry, torsion angle dynamics, molecular dynamics
Chemical shifts: BMR17484  
Expression system: Escherichia coli