› 2l81

Solution NMR

Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A

Released:
DOI: 10.2210/pdb2l81/pdb
PDB entry 2l81 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l81 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l81 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu G, Xiao R, Huang YJ, Patel D, Ciccosanti CT, Acton TB, Tong S, Everett JT, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172021 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enhancer of filamentation 1 p55 Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 20.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14511 (Residues: 399-563; Coverage: 20%)
Gene names: CASL, NEDD9
Sequence domains: Serine rich protein interaction domain
Structure domains: Serine-rich domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: distance geometry, simulated annealing, molecular dynamics
Expression system: Escherichia coli

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