PDBe 2l40

Solution NMR

Mouse prion protein (121-231) containing the substitution Y169A

Released:
Source organism: Mus musculus
Primary publication:
Cellular prion protein conformation and function.
Proc. Natl. Acad. Sci. U.S.A. 108 17308-13 (2011)
PMID: 21987789

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.32 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04925 (Residues: 120-231; Coverage: 48%)
Gene names: Prn-p, Prnp, Prp
Structure domains: Prion/Doppel protein, beta-ribbon domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: torsion angle dynamics
Chemical shifts: BMR17213  
Expression system: Escherichia coli