› 2kj4

Solution NMR

Solution structure of the complex of VEK-30 and plasminogen kringle 2

Released:
DOI: 10.2210/pdb2kj4/pdb
PDB entry 2kj4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kj4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kj4 coloured by chain, ensemble of 20 models, top view.
Source organisms:
Primary publication:
Solution structure of the complex of VEK-30 and plasminogen kringle 2.
Wang M, Zajicek J, Geiger JH, Prorok M, Castellino FJ
J Struct Biol 169 349-59 (2010)
PMID: 19800007

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162824 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
plasminogen Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 10.17 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
Structure domains: Plasminogen Kringle 4
Plasminogen ligand VEK-30 domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 32 amino acids
Theoretical weight: 3.78 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6V4L8 (Residues: 85-113; Coverage: 8%)
Sequence domains: Plasminogen (Pg) ligand in fibrinolytic pathway

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression systems:
  • Komagataella pastoris
  • Escherichia coli

Quick links

Citations

12 citation in other articles

Direct Host Plasminogen Binding to Bacterial Surface M-protein in Pattern D Strains of Streptococcus pyogenes Is Required for Activation by Its Natural Coinherited SK2b Protein.
Chandrahas et al. (2015)
11 more

3 mentions without citation

Solution structure of the complex of VEK-30 and plasminogen kringle 2.
Wang et al. (2010)
2 more