2kih

Solution NMR

S31N mutant of M2 proton channel

Released:
Primary publication:
Mechanism of drug inhibition and drug resistance of influenza A M2 channel.
Proc Natl Acad Sci U S A 106 7379-84 (2009)
PMID: 19383794

Function and Biology Details

Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143669 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 43 amino acids
Theoretical weight: 5.04 KDa
Source organism: Influenza A virus (A/Udorn/307/1972(H3N2))
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DOF5 (Residues: 18-60; Coverage: 44%)
Gene name: M
Sequence domains: Influenza Matrix protein (M2)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli