PDBe 2kb8

Solution NMR

The dynamic alpha-helix structure of micelle-bound human amylin.

Released:
Source organism: Homo sapiens
Primary publication:
Dynamic alpha-helix structure of micelle-bound human amylin.
J. Biol. Chem. 284 11982-91 (2009)
PMID: 19244249

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Islet amyloid polypeptide Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 3.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10997 (Residues: 34-70; Coverage: 55%)
Gene name: IAPP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli