Solution NMR

Solution Structure of FOXO3a Forkhead domain


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Forkhead box protein O3 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O43524 (Residues: 151-251; Coverage: 15%)
Gene names: FKHRL1, FOXO3, FOXO3A
Sequence domains: Forkhead domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: simulated annealing
Chemical shifts: BMR15939  
Expression system: Escherichia coli