2k40

Solution NMR

NMR structure of HESX-1 homeodomain double mutant R31L/E42L

Released:
Source organism: Homo sapiens
Entry authors: Asensio J, Torrado M, Gonzalez C, Bastida A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox expressed in ES cells 1 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 8.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBX0 (Residues: 108-174; Coverage: 36%)
Gene names: HANF, HESX1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli