Solution NMR

Solution NMR structure of the chromo domain of the chromobox protein homolog 4

Source organism: Homo sapiens
Entry authors: Kaustov L, Lemak A, Quyang H, Fares C, Gutmanas A, Ravichandran M, Loppnau P, Bountra C, Weigelt J, Edwards AM, Min J, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
E3 SUMO-protein ligase CBX4 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O00257 (Residues: 8-65; Coverage: 10%)
Gene name: CBX4
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: molecular dynamics
Chemical shifts: BMR15695  
Expression system: Escherichia coli