2k00

Solution NMR

Solution structure of the talin F3 in complex with layilin cytodomain

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.53 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P54939 (Residues: 309-400; Coverage: 4%)
Gene names: TLN, TLN1
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Layilin Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.82 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8C351 (Residues: 367-381; Coverage: 4%)
Gene name: Layn

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression systems:
  • Escherichia coli BL21
  • Not provided