2jhl

X-ray diffraction
1.75Å resolution

Structure of globular heads of M-ficolin complexed with sialic acid

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ficolin-1 Chain: F
Molecule details ›
Chain: F
Length: 218 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O00602 (Residues: 109-326; Coverage: 73%)
Gene names: FCN1, FCNM
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: R3
Unit cell:
a: 72.93Å b: 72.93Å c: 124.83Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.21 0.24
Expression system: Trichoplusia ni