2jg9

X-ray diffraction
1.9Å resolution

Crystallographic structure of human C1q globular heads (P1)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C1q subcomponent subunit A Chains: A, D
Molecule details ›
Chains: A, D
Length: 134 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02745 (Residues: 112-245; Coverage: 60%)
Gene name: C1QA
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit B Chains: B, E
Molecule details ›
Chains: B, E
Length: 136 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02746 (Residues: 118-253; Coverage: 60%)
Gene name: C1QB
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit C Chains: C, F
Molecule details ›
Chains: C, F
Length: 131 amino acids
Theoretical weight: 14.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02747 (Residues: 115-245; Coverage: 60%)
Gene names: C1QC, C1QG
Sequence domains: C1q domain
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P1
Unit cell:
a: 48.15Å b: 48.24Å c: 87.79Å
α: 92.45° β: 92.65° γ: 113.53°
R-values:
R R work R free
0.219 0.214 0.26