2jas

X-ray diffraction
2.7Å resolution

Structure of deoxyadenosine kinase from M.mycoides with bound dATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + deoxyguanosine = ADP + dGMP
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dNK domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 206 amino acids
Theoretical weight: 24.43 KDa
Source organism: Mycoplasma mycoides subsp. mycoides SC
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q93IG4 (Residues: 1-205; Coverage: 100%)
Gene name: dGUOK
Sequence domains: Deoxynucleoside kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 190.845Å b: 100.85Å c: 109.486Å
α: 90° β: 124.58° γ: 90°
R-values:
R R work R free
0.235 0.233 0.274
Expression system: Escherichia coli BL21(DE3)