2jaq

X-ray diffraction
2.3Å resolution

Structure of deoxyadenosine kinase from M. mycoides with bound dCTP

Released:

Function and Biology Details

Reaction catalysed:
ATP + deoxyguanosine = ADP + dGMP
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dNK domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 205 amino acids
Theoretical weight: 24.29 KDa
Source organism: Mycoplasma mycoides subsp. mycoides SC
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q93IG4 (Residues: 1-205; Coverage: 100%)
Gene name: dGUOK
Sequence domains: Deoxynucleoside kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P31
Unit cell:
a: 84.527Å b: 84.527Å c: 53.603Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.234 0.233 0.263
Expression system: Escherichia coli BL21(DE3)