2iom

X-ray diffraction
2Å resolution

Mouse p53 core domain soaked with 2-propanol

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P02340 (Residues: 92-292; Coverage: 52%)
Gene names: P53, Tp53, Trp53
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 92.299Å b: 44.541Å c: 62.915Å
α: 90° β: 126.23° γ: 90°
R-values:
R R work R free
0.209 0.209 0.246
Expression system: Escherichia coli BL21