X-ray diffraction
2Å resolution

Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP

Source organism: Trypanosoma brucei

Function and Biology Details

Reaction catalysed:
UTP + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Terminal uridylyltransferase 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 353 amino acids
Theoretical weight: 39.88 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q381M1 (Residues: 1-333; Coverage: 100%)
Gene names: TUT4, Tb11.01.7300
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 78.773Å b: 41.525Å c: 103.792Å
α: 90° β: 94.94° γ: 90°
R R work R free
0.228 0.228 0.275
Expression system: Escherichia coli BL21(DE3)