2ihc

X-ray diffraction
2.44Å resolution

Crystal structure of the bric-a-brac (BTB) domain of human BACH1

Released:
Source organism: Homo sapiens
Entry authors: Amos AL, Turnbull AP, Bunkoczi G, Papagrigoriou E, Gorrec F, Umeano C, Bullock A, von Delft F, Weigelt J, Edwards A, Arrowsmith C, Sundstrom M, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription regulator protein BACH1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 124 amino acids
Theoretical weight: 14.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14867 (Residues: 7-128; Coverage: 17%)
Gene name: BACH1
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 83.44Å b: 53.664Å c: 123.891Å
α: 90° β: 106.15° γ: 90°
R-values:
R R work R free
0.248 0.247 0.278
Expression system: Escherichia coli