X-ray diffraction
2.4Å resolution

Crystal Structure of the First and Second FNIII Domains of Ihog

Source organism: Drosophila melanogaster
Primary publication:
Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc. Natl. Acad. Sci. U.S.A. 103 17208-13 (2006)
PMID: 17077139

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Interference hedgehog Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 24.16 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
  • Canonical: Q9VM64 (Residues: 466-676; Coverage: 24%)
Gene names: CG9211, ihog
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P212121
Unit cell:
a: 39.38Å b: 65.24Å c: 84.21Å
α: 90° β: 90° γ: 90°
R R work R free
0.244 0.244 0.275
Expression system: Escherichia coli