PDBe 2i5c

X-ray diffraction
1.75Å resolution

Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,4,5)P5

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pleckstrin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 109 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: P08567 (Residues: 244-347)
Gene names: P47, PLEK

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: C2
Unit cell:
a: 82.501Å b: 47.604Å c: 87.622Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.176 0.243
Expression system: Escherichia coli BL21(DE3)