2i4i

X-ray diffraction
2.2Å resolution

Crystal Structure of human DEAD-box RNA helicase DDX3X

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent RNA helicase DDX3X Chain: A
Molecule details ›
Chain: A
Length: 417 amino acids
Theoretical weight: 47.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00571 (Residues: 168-582; Coverage: 63%)
Gene names: DBX, DDX3, DDX3X
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P3121
Unit cell:
a: 67.288Å b: 67.288Å c: 253.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.187 0.218
Expression system: Escherichia coli BL21(DE3)